Mammary Tumor Development in Mice Ovariectomized at Birth
نویسندگان
چکیده
منابع مشابه
Genetic analysis of mammary tumor induction and expression of mammary tumor virus antigen in hormone-treated ovariectomized GR mice.
Early stages of mammary tumors (EMT) were induced with a combined treatment of progesterone (P) and estrone (E) in ovariectomized adult GRS/A (GR) mice, a strain of European origin and with a high incidence of mammary cancer. The mammary tumors were comparable to the pregnancy-dependent tumors of breeding females of this strain. The hormone treatment did not lead to EMT in a variety of other st...
متن کاملImmunization of mice against murine mammary tumor virus infection and mammary tumor development.
Formalin-inactivated whole murine mammary tumor virus (MuMTV), VuMTV membranes, the acid-soluble component of MuMTV, and purified MuMTV glycoprotein with a molecular weight of 55,000 (gp55; also designated as gp52) were used as vaccines in an attempt to identify the MuMTV antigen(s) that can protect mice from exogenous MuMTV infection and subsequent tumor development. Formalin-inactivated whole...
متن کاملMortality in premature mice at birth and during neonatal development.
This paper reports a statistical study of mortality in about 2 500 premature mice at birth and during neonatal development. The premature mice were removed by caesarean section and reanimated for 30 min.; surviving mice as well as newborns delivered vaginally on day 20 of pregnancy (control mice) were raised from birth to day 20 by nursing mothers spontaneously delivered at the same time. The m...
متن کاملMammary fat pad tumor preparation in mice.
The host microenvironment influences tumor biology, affecting parameters such as gene expression, angiogenesis, growth, invasion, metastasis, and responses to therapy. Consequently, the use of tumor models growing in appropriate orthotopic locations is necessary to obtain a rigorous understanding of tumor pathophysiology and to correctly study antitumor treatments. The mouse mammary fat pad ser...
متن کاملstudy of biological characteristics and incidence of spontaneous mammary tumor in razi mice, a worthwhile model for mammary, iranian origin
razi mouse is originally established from native iranian mice at razi institute and is susceptible to spontaneous mammary tumor. in this study, incidence, age and predisposing factors of tumor and some of biological characteristics of this strain were studied. there were significant differences in incidence of mammary tumor in razi virgin females as compared with normally breeding and hormone t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1939
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.25.6.277